Transtympanic gentamicin: Experience in Hospital Clínico Universidad de Chile

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Karen García C.
Pablo Cantillano P.
Natalia Cabrera S.
Paul Délano R.

Keywords

Vertigo, dizziness, gentamicin, Méniere disease, endolymphatic hydrops

Abstract

Introduction: Transtympanic gentamicin is used for treatment of patients with chro- nic vertigo refractory to medical management. Aim: To describe and analyze the clinical outcome of patients whom underwent treatment with transtympanic gentamicin at the Clinical Hospital Universidad de Chile. Material and method: Retrospective and descriptive study including patients with oto- laryngologist disease whom underwent treatment with transtympanic gentamicin between 2008 and 2018. Epidemiological, clinical variables and vestibular function were analyzed. Results: The serie consists of ten patients, 7 men and 3 women, with an average age of 52,4years. The most frequent diagnosis was Méniere disease (7patients). The avera- ge number of gentamicin injections was 2,8. The follow up varies from 1 to 96 months, presenting improvement of vertigo in the majority of the cases (8 of 10 patients). Conclusion: The treatment with transtympanic injections of gentamicin is a relevant option to decrease symptoms in patients with chronic intractable vertigo. It should be indicated in selected patients. Prior and posterior the treatment, patients must be stu- died with a complete evaluation of the auditory and vestibular function.

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